相关实验视频

Updated: Feb 7, 2026

Dosimetry for Cell Irradiation using Orthovoltage 40-300 kV X-Ray Facilities

Dosimetry for Cell Irradiation using Orthovoltage 40-300 kV X-Ray Facilities

Published on: February 20, 2021

一个基于物理学的神经网络,用于使用定量辐射声学成像进行体内剂量测量

Leshan Sun, Kristina Bjegovic, Lucia Rodriguez-Gonzalez

Research square

|February 6, 2026

概括

现在可以在体内使用定量放射声学成像 (qRAI) 进行精确的放射治疗剂量测量. 这种新的物理信息神经网络 (PINN) 框架可以直接在患者内部实时进行定量剂量映射.

科学领域:

医学物理医学物理
生物医学成像技术生物医学成像技术
人工智能在医学中的应用

背景情况:

精确的体内剂量测量对于放射治疗至关重要,但目前缺乏直接的临床测量方法.
放射声学成像 (RAI) 通过检测辐射的声波来显示剂量监测的潜力,但仅限于定性评估.

研究的目的:

开发和验证使用物理信息神经网络 (PINN) 在体内剂量重建的定量RAI (qRAI) 框架.
为了实现实时的定量剂量映射,在放射治疗期间直接在患者体内进行.

主要方法:

开发了一个基于物理学的神经网络 (PINN),集成声波物理和辐射传递和检测系统的数字双胞胎.
PINN从有限视野的声学数据中重建定量剂量图,与实验和模拟剂量参考进行校准.
在各种场景中进行了验证,包括水箱,人体干幻象和FLASH电子疗法.

主要成果:

基于PINN的qRAI框架成功地在体内重建了定量剂量图.
与纯粹数据驱动模型相比,该方法显示出更高的稳定性和通用性,特别是在没有实验基础真相的环境中.
在各种临床和实验设置中实现了准确的剂量映射.

结论:

基于PINN的qRAI为实时,自适应和定量体内剂量测量提供了强大的工具.
这项技术解决了在放射治疗期间直接,准确的剂量测量的关键需求.
该框架显示了改善放射治疗安全性和疗效的重大前景.

更多相关视频

Deep Neural Networks for Image-Based Dietary Assessment

Deep Neural Networks for Image-Based Dietary Assessment

Published on: March 13, 2021

In Vivo Imaging and Quantitation of the Host Angiogenic Response in Zebrafish Tumor Xenografts

In Vivo Imaging and Quantitation of the Host Angiogenic Response in Zebrafish Tumor Xenografts

Published on: August 14, 2019

相关概念视频

Protein Networks

Protein Networks

An organism can have thousands of different proteins, and these proteins must cooperate to ensure the health of an organism. Proteins bind to other proteins and form complexes to carry out their functions. Many proteins interact with multiple other proteins creating a complex network of protein interactions.
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...

Protein Networks

Protein Networks

Network Covalent Solids

Network Covalent Solids

Network covalent solids contain a three-dimensional network of covalently bonded atoms as found in the crystal structures of nonmetals like diamond, graphite, silicon, and some covalent compounds, such as silicon dioxide (sand) and silicon carbide (carborundum, the abrasive on sandpaper). Many minerals have networks of covalent bonds.
To break or to melt a covalent network solid, covalent bonds must be broken. Because covalent bonds are relatively strong, covalent network solids are typically...

Physical and Chemical Properties of Matter

Physical and Chemical Properties of Matter

The characteristics that enable us to distinguish one substance from another are called properties.

Physical Pendulum

Physical Pendulum

When a rigid body is hanging freely from a fixed pivot point and is displaced, it oscillates similar to a simple pendulum and is known as a physical pendulum. The period and angular frequency of a physical pendulum are obtained by using the small-angle approximation and drawing parallels with a spring-mass system. The small-angle approximation (sinθ=θ) is valid up to about 14°.
When dealing with complicated systems, the mass moment of inertia is an important parameter, as it...

The Scope of Physics

The Scope of Physics

Physics is concerned with the interactions of energy, matter, space, and time, in order to discover the underlying mechanisms that underpin all phenomena. The word "physics" comes from the Greek word "phúsis", which means nature. Physics seeks to comprehend the natural world around us at its most fundamental level. It emphasizes the use of quantitative laws to do this, which could be valuable in other fields that want to push the performance boundaries of present...