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Updated: Feb 7, 2026

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解读H19在胆固醇性肝损伤中的作用 使用snRNA-seq,空间转录学和基于机器学习的疾病预测

Grayson Welch Way, Xixian Jiang, Hongkun Lu

    Research square
    |February 6, 2026
    PubMed
    概括

    长非编码RNA H19通过促进致病性胆管细胞状态来驱动原发性硬化胆管炎 (PSC). 删除H19 (H19删除) 可减轻肝损伤并恢复正常的信号传输,使H19成为PSC的治疗点.

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