相关实验视频
Updated: Jul 11, 2026

09:41
Reconstitution Of β-catenin Degradation In Xenopus Egg Extract
Published on: June 17, 2014
概括
这项研究纠正了先前发表的一篇文章DOI. 校正确保了准确的引用和引用,以确保科学完整性.
科学领域:
- 科学出版科学出版
- 学术传播学术交流
背景情况:
- 科学文献的准确性至关重要.
- 适当的引用确保了研究的完整性.
研究的目的:
- 为了纠正发表文章的数字对象标识符 (DOI) 中的错误.
- 在科学数据库中保持准确的记录.
主要方法:
- 识别错误的DOI. 这是一个错误的DOI.
- 发出正确的DOI的纠正通知.
主要成果:
- 这篇文章的DOI已更新至10.1016/j.igie.2023.07.002.
- 确保正确的链接到已发表的作品.
结论:
- 准确的DOI对于科学文章的可发现性和可追溯性至关重要.
- 这次校正符合学术出版的标准.
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Overview
Proofreading
Synthesis of new DNA molecules starts when DNA polymerase links nucleotides together in a sequence that is complementary to the template DNA strand. DNA polymerase has a higher affinity for the correct base to ensure fidelity in DNA replication. The DNA polymerase furthermore proofreads during replication, using an exonuclease domain that cuts off incorrect nucleotides from the nascent DNA strand.Errors during Replication Are Corrected by the DNA Polymerase EnzymeGenomic DNA is synthesized in...
Proofreading
Synthesis of new DNA molecules is carried out by the enzyme DNA polymerase, which adds nucleotides on the daughter strand complementary to the template DNA strand. DNA polymerase has a higher affinity to add the correct base and ensures fidelity during DNA replication. Furthermore, it exhibits proofreading activity during replication, using an exonuclease domain that cuts off incorrect nucleotides from the nascent DNA strand.
Errors During Replication are Corrected by the DNA Polymerase Enzyme
Errors During Replication are Corrected by the DNA Polymerase Enzyme
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Organisms are capable of detecting and fixing nucleotide mismatches that occur during DNA replication. This sophisticated process requires identifying the new strand and replacing the erroneous bases with correct nucleotides. Mismatch repair is coordinated by many proteins in both prokaryotes and eukaryotes.
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The Mutator Protein Family Plays a Key Role in DNA Mismatch Repair
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