在英语和西班牙语的拉丁裔中,蒙特利尔认知评估的最佳切线
medRxiv : the preprint server for health sciences
|February 6, 2026
概括
新的蒙特利尔认知评估 (MoCA) 切断措施提高了美国拉丁裔人口认知障碍查的准确性. 最佳得分因语言,年龄和教育而异,提供更好的人口群体代表性.
科学领域:
- 神经科学是一个神经科学.
- 老年学是指老年学的学科.
- 心理测量 心理测量 心理测量
背景情况:
- 蒙特利尔认知评估 (MoCA) 是用于查认知障碍的常见工具.
- 现有的MoCA截止分数表明美国拉丁裔人口的表现不佳.
- 之前的研究存在一些局限性,包括小样本大小和组合诊断组.
研究的目的:
- 为了确定特别针对美国拉丁裔的轻度认知障碍 (MCI) 和痴呆症的最佳MoCA截止分数.
- 通过分析更大,更多样化的样本并考虑人口因素来解决先前研究的局限性.
主要方法:
- 来自国家阿尔茨海默氏症协调中心统一数据集的横截面数据的分析.
- 包括英语和西班牙语的拉丁裔参与者在他们的主要语言中进行测试.
- 通过测试语言,年龄和教育水平进行分层,使用Youden指数进行诊断准确性和ROC分析.
主要成果:
- 在西班牙语测试的参与者,75岁以上的参与者和受教育程度较低的人群中,最佳的MoCA截止值较低.
- 曲线下的面积 (AUC) 值表明在区分认知不受损 (CU) 与MCI和MCI与痴呆症之间具有良好的诊断准确性.
- 研究结果表明,标准切断可能会错误地分类美国拉丁裔子组中的认知状态.
结论:
- 该研究提供了针对美国拉丁裔人口量身定制的精细的MoCA截止分数,考虑到语言和人口统计学.
- 这些优化的切断值提高了这一人口群体认知障碍查的准确性.
- 一个分数计算器可用于临床和研究应用.
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