相关实验视频
Updated: Feb 7, 2026

13:01
Anti-Nuclear Antibody Screening Using HEp-2 Cells
Published on: June 23, 2014
137.4K
病例报告:儿童反复出现抗谷氨酸脱化酶65抗体相关脑炎
Pingping Tian1,2, Juan Li1,2, Yong Liu1,2
1Neurology department, Children's Hospital Affiliated to Shandong University, Jinan, Shandong, China.
Frontiers in immunology
|February 6, 2026
概括
本案例研究详细介绍了儿童中反复出现的抗谷氨酸脱酶65 (GAD65) 抗体相关脑炎. 利图西马布在治疗这种罕见的神经疾病方面被证明是有效的,为管理复发提供了希望.
科学领域:
- 神经学 神经学
- 免疫学 免疫学 免疫学
- 儿科 儿科 儿科
背景情况:
- 自身免疫性脑炎呈现出各种神经系统症状.
- 抗谷氨酸脱酶65 (GAD65) 抗体相关脑炎是一种罕见的自身免疫性疾病.
- 儿科患者的复发病例需要特定的诊断和治疗策略.
研究的目的:
- 描述儿科患者反复复发的抗GAD65抗体相关脑炎的临床特征.
- 为了提高对儿童这种罕见的神经疾病的了解.
- 为了评估反复复发的抗GAD65抗体相关脑炎的治疗结果.
主要方法:
- 一个儿科患者的临床数据的回顾性分析.
- 对神经成像 (MRI),脑电图 (EEG) 和脑脊液 (CSF) 发现的审查.
- 对甲基prednisolone,静脉注射免疫球蛋白和rituximab的治疗反应的评估.
主要成果:
- 患者经历了脑炎的反复发作,带有各种神经症状,包括发作和认知衰退.
- 在初始诊断和复发期间,在血清和脑脊液中检测到抗GAD65抗体.
- 甲基prednisolone和免疫球蛋白的治疗显示出初始改善,而rituximab在管理复发方面是有效的.
结论:
- 儿科患者反复出现的抗GAD65抗体相关脑炎表现出复杂的临床特征.
- 利图西马布是治疗复发性抗GAD65抗体相关脑炎的潜在治疗选择.
- 早期诊断和量身定制的治疗对于儿童自身免疫脑炎的良好结果至关重要.
更多相关视频
相关概念视频
Oxidation of Alkenes: Anti Dihydroxylation with Peroxy Acids
7.4K
Diols are compounds with two hydroxyl groups. In addition to syn dihydroxylation, diols can also be synthesized through the process of anti dihydroxylation. The process involves treating an alkene with a peroxycarboxylic acid to form an epoxide. Epoxides are highly strained three-membered rings with oxygen and two carbons occupying the corners of an equilateral triangle. This step is followed by ring-opening of the epoxide in the presence of an aqueous acid to give a trans diol.
7.4K
Amino acids
105.7K
Amino acids are the monomers that comprise proteins. Each amino acid has the same fundamental structure, which consists of a central carbon atom, or the alpha (α) carbon, bonded to an amino group (NH2), a carboxyl group (COOH), and to a hydrogen atom. Every amino acid also has another atom or group of atoms bonded to the central atom known as the R group. There are 20 common amino acids present in proteins, each with a different R group. Variation in the amino acid sequence is responsible for...
105.7K
Antiepileptic Drugs: Glutamate Antagonists
996
Glutamate is a fundamental neurotransmitter in the central nervous system, playing a vital role in neuronal communication and various cognitive processes. Glutamate stands as the principal excitatory neurotransmitter in the brain. Its presence is crucial for the communication between neurons, underpinning essential processes such as synaptic transmission, neuronal excitability, and plasticity. These functions are vital for higher-order cognitive processes, including learning and memory. The...
996
Data Reporting and Recording
5.5K
Reporting and recording are crucial in data documentation. The timely, thorough, and accurate documentation of facts is essential when recording patient data. Failure to record findings during an assessment or interpretation of a problem will result in loss of information and make the patient document unreliable. The reader is left with general impressions if the information is not specific. A recording is documenting data of the individual's health information in a traceable, secure, and...
5.5K
Antibody Structure
65.6K
Overview
Antibodies, also known as immunoglobulins (Ig), are essential players of the adaptive immune system. These antigen-binding proteins are produced by B cells and make up 20 percent of the total blood plasma by weight. In mammals, antibodies fall into five different classes, which each elicits a different biological response upon antigen binding.
The Y-Shaped Structure of Antibodies Consists of Four Polypeptide Chains
Antibodies consist of four polypeptide chains: two identical heavy...
Antibodies, also known as immunoglobulins (Ig), are essential players of the adaptive immune system. These antigen-binding proteins are produced by B cells and make up 20 percent of the total blood plasma by weight. In mammals, antibodies fall into five different classes, which each elicits a different biological response upon antigen binding.
The Y-Shaped Structure of Antibodies Consists of Four Polypeptide Chains
Antibodies consist of four polypeptide chains: two identical heavy...
65.6K
Types of Reports I: Hands-off Report
1.5K
A hand-off report, also known as a change-of-shift report, is a crucial nursing process that ensures the smooth transition of patient care responsibilities between nursing staff.
Following are the key components and categories of hand-off reports:
Purpose and Process:
Following are the key components and categories of hand-off reports:
Purpose and Process:
1.5K

