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Updated: Feb 7, 2026

In Vitro Selection of Engineered Transcriptional Repressors for Targeted Epigenetic Silencing
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Published on: May 5, 2023

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对联合抗逆转录病毒疗法的转录反应预测了副作用和新的目标

Alexander Lachmann1,2,3, Letizia Amadori4,5, Paola Nicoletti5

  • 1Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, United States.

Frontiers in pharmacology
|February 6, 2026
PubMed
概括

与单一药物相比,抗逆转录病毒疗法 (ART) 组合疗法表现出不同的基因表达特征,影响HIV与宿主相互作用,并可能提高安全性. 这项研究有助于开发更安全,更有效的HIV治疗方法.

关键词:
在LINCS L1000中使用LINCS.药物对药物的不良影响抗逆转录病毒药物治疗方法在Silico预测预测.在体外细胞系治疗过程中.转录基因分析的概况

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