全身麻醉和/或深度催眠状态在基于普罗波的意识镇静中进行内镜检查
Halim Bou Daher1, Ali El Mokahal1, Mohamad Ali Ibrahim1
1Division of Gastroenterology, Department of Internal Medicine, American University of Beirut Medical Center, Beirut, Lebanon.
iGIE : innovation, investigation and insights
|February 6, 2026
概括
许多内镜患者经历全身麻醉 (GA) 或深度催眠状态,超过中度镇静目标. 酒精使用预测了更深的镇静,而年轻的年龄预测了更轻的GA,并且观察到术后的增加.
科学领域:
- 麻醉学 麻醉学
- 胃肠病学 胃肠病学
- 临床监测 临床监测
背景情况:
- 适度镇静是内镜的目标,但实际达到的深度没有得到充分记录.
- 通常使用基于普罗波的镇静剂,但其深度需要精确的监测.
研究的目的:
- 为了评估总麻醉 (GA) 或深度催眠状态的发生率和持续时间,在用于内镜的基于propofol的镇静期间.
- 确定与超过中度镇静水平相关的预测因素和后果.
主要方法:
- 一项前性队列研究,涉及95名在同一天接受双向内镜检查的患者.
- 双光谱指数 (BIS) 监测被用来量化镇静深度,将GA定义为BIS <60和深度催眠状态作为BIS <40.
- 收集了包括饮酒量和年龄在内的患者数据,并评估了手术后的结果.
主要成果:
- 88%的患者经历了BIS得分<60 (GA),12.6%的得分<40 (深度催眠状态).
- 显著的酒精使用预测了更深的镇静 (BIS <40),而年轻的年龄预测了更轻的GA (BIS <60).
- 患有BIS<40的患者报告了更高的手术后头率.
结论:
- 在接受内镜检查的患者中,很大一部分患者经历的镇静比预期的更深.
- 虽然酒精使用和年轻的年龄与更深的镇静有关,但在多变量分析中没有确定确定的预测因素.
- 需要进一步的研究来了解深度镇静的预测因素和后果,并改进监测技术.
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