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Updated: Feb 7, 2026

Epigenetic Regulation of Cardiac Differentiation of Embryonic Stem Cells and Tissues
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在斑马鱼模型中,Mef2d通过表观遗传调制来调节IgZ和IgM同型的相互排斥表达

Jianfei Ji1, Nan Zhang1, Chongbin Hu1

  • 1College of Life Sciences, Key Laboratory for Cell and Gene Engineering of Zhejiang Province, Zhejiang University, Hangzhou 310058, China.

Fundamental research
|February 6, 2026
PubMed
概括

肌细胞增强因子2D (Mef2d) 调节了teleosts中的免疫球蛋白Z (IgZ) 基因组合. Mef2d在表观遗传上沉默免疫球蛋白M (IgM) 位点,通过一种新的机制确保独家IgZ的产生.

关键词:
凝聚力复杂的凝聚力复杂.表观遗传调节 表观遗传调节独家表达的独家表达在IgZ同型中,同型是IgZ.这就是Mef2d的意思.这是一个Sin3/Hdac1复合体.

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