试点研究比较了一种新的EUS引导的机动化活检针技术与传统采样
David W Dornblaser1, Iyad Khamaysi2, Seth A Gross1
1Department of Gastroenterology and Hepatology, NYU Langone Health, New York, New York, USA.
iGIE : innovation, investigation and insights
|February 6, 2026
概括
与手动针相比,一种新的机动内镜超声波引导细针活检 (EUS-FNB) 装置改善了胰腺瘤的组织获取速度和组织质量. 这种自动化方法通过增强瘤概况,对精准医学有希望.
科学领域:
- 胃肠病学和内镜检查
- 在瘤学瘤学.
- 医疗器械 医疗器械
背景情况:
- 透视超声引导细针活检 (EUS-FNB) 对于精密医学中的组织学诊断和分子分析至关重要.
- 目前手动活检针面临的样品质量限制是由于技术和针头操纵.
- 优化组织获取对于准确的瘤表征至关重要.
研究的目的:
- 为了比较一种新型的机动EUS-FNB设备 (Precision) 和一种传统的手动设备 (SharkCore),用于在固体胰腺瘤中获取组织.
- 为了评估手术时间,投次数,诊断产量和组织学质量的差异.
- 评估自动化EUS-FNB在改善瘤采样方面的潜力.
主要方法:
- 一项试点研究涉及患有固体胰腺瘤的患者.
- 每位患者都使用Precision机动设备和SharkCore手动设备进行了组织采样.
- 关键指标包括手术时间,传球和投球数量,诊断产量和组织学分数.
主要成果:
- 机动精密装置显著减少了组织采样时间 (3.87分钟与5.64分钟相比,P=.001),以及投次数 (5与55相比,P=.00002).
- 这两种设备的诊断产量在两种设备之间是可比的.
- 与SharkCore (3.2/5,P=.002) 相比,Precision设备获得了更高的平均组织学得分 (4.6/5).
结论:
- 自动化机动化EUS-FNB采样可以提高瘤分子分析的组织学质量和一致性.
- 精密装置证明了减少手术时间和减少针头操纵的潜力.
- 需要进行更大规模的研究来验证在临床实践中对自动化EUS-FNB的这些发现.
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