癌症患者的现实世界行为实践:误解危及日常生活活动
E Shachar1,2, S Peleg-Hasson1,2, D Vorobiof3
1Faculty of Medicine, Tel Aviv University, Tel Aviv.
概括
全球大多数癌症患者由于对治疗和疾病的误解,在日常生活活动 (DLA) 中经历了限制. 在临床试验中评估DLA对于改善患者的状况至关重要.
科学领域:
- 在瘤学瘤学.
- 患者报告的结果.
- 生活质量研究生活质量研究
背景情况:
- 与健康相关的生活质量 (HRQoL) 衡量症状,而不是日常生活活动 (DLA).
- 在癌症患者中开发并验证了一种日常生活评估工具.
- 以前的发现表明,癌症患者的日常活动受到损害.
研究的目的:
- 在国际癌症患者队列中检查日常生活活动 (DLA).
- 识别与日常生活中的限制相关的因素.
- 倡导DLA作为额外的临床试验终点.
主要方法:
- 通过Belong.life数字健康平台在国际上分发的问卷被使用.
- 检查了现实世界患者报告的实践,包括人口统计学,临床和行为参数.
- 分析了来自1395名患者报告的结果的数据.
主要成果:
- 73%的患者报告说日常活动受到限制;22%的患者维持了超过一半的这些限制.
- 常见的限制包括避免阳光照射,国际旅行和公共场所.
- 年龄较小,女性性别和原发性癌症部位与更严格的日常生活限制有关.
结论:
- 全球大多数癌症患者面临的日常活动受到损害,可能是由于错误信息.
- 日常生活活动 (DLA) 是生活质量的一个被忽视的方面.
- 将DLA评估纳入临床试验可以提高患者的福祉和治疗结果.
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