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Updated: Feb 7, 2026

Human Peripheral Blood Neutrophil Isolation for Interrogating the Parkinson's Associated LRRK2 Kinase Pathway by Assessing Rab10 Phosphorylation
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Human Peripheral Blood Neutrophil Isolation for Interrogating the Parkinson's Associated LRRK2 Kinase Pathway by Assessing Rab10 Phosphorylation

Published on: March 21, 2020

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炎症信号在人类和小鼠之间差异性地改变了染色质可访问性和PD相关激酶LRRK2的基因表达

Alexandra Beilina, Jae-Hyeon Park, Natalie Landeck

    bioRxiv : the preprint server for biology
    |February 6, 2026
    PubMed
    概括

    炎症通过干扰素-马信号来激活人体微质中的富含白素的重复激酶2 (LRRK2). 这突显了物种特异性基因调节对于模拟帕金森病和克罗恩病等疾病至关重要.

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    Assaying the Kinase Activity of LRRK2 in vitro06:09

    Assaying the Kinase Activity of LRRK2 in vitro

    Published on: January 18, 2012

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