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Updated: Feb 7, 2026

In Vitro Aggregation Assays Using Hyperphosphorylated Tau Protein
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Published on: January 2, 2015

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在P301S鼠中,Wasf1的除减轻了的高酸化,微质状态过渡和认知缺陷

Clara Berdasco, Woo-Hyun Cho, Jordan Lee

    bioRxiv : the preprint server for biology
    |February 6, 2026
    PubMed
    概括

    在阿尔茨海默氏症模型中抑制WAVE1减少了tau病理和认知衰退. 在鼠中删除WAVE1基因 (Wasf1) 恢复了微质功能,缓解了疾病的进展.

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