相关实验视频

Updated: Feb 7, 2026

Establishment of a High-throughput Setup for Screening Small Molecules That Modulate c-di-GMP Signaling in Pseudomonas aeruginosa
11:31

Establishment of a High-throughput Setup for Screening Small Molecules That Modulate c-di-GMP Signaling in Pseudomonas aeruginosa

Published on: June 30, 2016

9.2K

在Actinomycetota中,c-di-GMP控制的西格玛因子的监管分歧和功能多样化

Joee D Denis, Govind Chandra, Justine J Choi

    bioRxiv : the preprint server for biology
    |February 6, 2026
    PubMed
    概括

    在Actinomycetota中发现的替代性西格玛因子WhiG已经从调节鞭毛基因多样化到控制各种过程,如化和抗生素生物合成. 它的调节也进化了,一些形式通过c-di-GMP与抗西格玛RsiG相互作用.

    更多相关视频

    Capture Compound Mass Spectrometry - A Powerful Tool to Identify Novel c-di-GMP Effector Proteins12:11

    Capture Compound Mass Spectrometry - A Powerful Tool to Identify Novel c-di-GMP Effector Proteins

    Published on: March 29, 2015

    12.1K
    Sigma's Non-specific Protease Activity Assay - Casein as a Substrate11:37

    Sigma's Non-specific Protease Activity Assay - Casein as a Substrate

    Published on: September 17, 2008

    78.6K

    相关概念视频

    Cis-regulatory Sequences02:02

    Cis-regulatory Sequences

    Cis-regulatory sequences are short fragments of non-coding DNA that are present on the same chromosomes as the genes that they regulate. These fragments serve as binding sites for transcriptional regulators, proteins that are responsible for controlling gene transcription and differential gene expression across cell types in eukaryotes. Cis-regulatory sequences can be close to the gene of interest or thousands of bases away in the DNA sequence; however, those sequences that are further away are...
    11.9K
    Cis-regulatory Sequences02:02

    Cis-regulatory Sequences

    4.2K
    Drug Control Governance: Regulatory Bodies and Their Impact01:03

    Drug Control Governance: Regulatory Bodies and Their Impact

    Drug control governance involves the oversight and regulation of pharmaceuticals to ensure their safety and efficacy while preventing illegal drug use and trafficking. Regulatory bodies, including the US Food and Drug Administration (FDA) and the European Union's European Medicines Agency (EMA), play a central role in this process. These agencies evaluate the safety and efficacy of drugs before they can be marketed. They fund clinical trials and assess the benefits and risks associated with...
    565
    Transcription Factors02:16

    Transcription Factors

    Tissue-specific transcription factors contribute to diverse cellular functions in mammals. For example, the gene for beta globin, a major component of hemoglobin, is present in all cells of the body. However, it is only expressed in red blood cells because the transcription factors that can bind to the promoter sequences of the beta globin gene are only expressed in these cells. Tissue-specific transcription factors also ensure that mutations in these factors may impair only the function of...
    82.8K
    Divergence and Curl01:15

    Divergence and Curl

    The divergence of a vector field at a point is the net outward flow of the flux out of a small volume through a closed surface enclosing the volume, as the volume tends to zero. More practically, divergence measures how much a vector field spreads out or diverges from a given point. For an outgoing flux, conventionally, the divergence is positive. The diverging point is often called the "source" of the field. Meanwhile, the negative divergence of a vector field at a point means that the vector...
    3.2K
    Divergence and Stokes' Theorems01:06

    Divergence and Stokes' Theorems

    The divergence and Stokes' theorems are a variation of Green's theorem in a higher dimension. They are also a generalization of the fundamental theorem of calculus. The divergence theorem and Stokes' theorem are in a way similar to each other; The divergence theorem relates to the dot product of a vector, while Stokes' theorem relates to the curl of a vector. Many applications in physics and engineering make use of the divergence and Stokes' theorems, enabling us to write...
    3.7K