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Updated: Feb 7, 2026

Electroporation of the Hindbrain to Trace Axonal Trajectories and Synaptic Targets in the Chick Embryo
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致病基因KIF1A变种差异性地破坏了轴突贩运,并阻碍了突触发育.

Jayne Aiken, Carris Borland, Nicolas Marotta

    bioRxiv : the preprint server for biology
    |February 6, 2026
    PubMed
    概括

    在KIF1A的突变扰乱了人类神经元的突触发育和功能,影响KIF1A相关的神经障碍 (KAND) 的发病. 不同的突变会导致明显的分子和功能缺陷,揭示KIF1AA.

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