微细胞表观遗传记忆与由预防性巨细胞衍生的小细胞外囊泡诱导的炎症性疼痛的加速分辨率有关

概括

巨细胞衍生的小细胞外囊泡 (sEVs) 通过重编程脊柱微质来加速炎症性疼痛的缓解. 这种效应需要微质细胞的存在,并涉及表观遗传修饰,为非成性疼痛预防提供了洞察力.

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