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Updated: Feb 7, 2026

Left Atrial Stenosis Induced Pulmonary Venous Arterialization and Group 2 Pulmonary Hypertension in Rat
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Published on: November 18, 2018

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失调的TGFβ-ERK信号驱动器 异常的细胞外基质生产 在诺南综合征相关的肺狭窄症中

Clifford Z Liu, Shrey Patel, Simone Sidoli

    bioRxiv : the preprint server for biology
    |February 6, 2026
    PubMed
    概括

    诺南综合征 (NS) 的遗传变异通过使膜细胞对TGFβ过敏而导致肺狭窄 (PVS),导致异常的细胞外基质 (ECM) 生产. 这项研究揭示了在NS患者中驱动PVS的一个关键机制.

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