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Updated: Feb 7, 2026

Improved Enzyme Protection Assay to Study Staphylococcus aureus Internalization and Intracellular Efficacy of Antimicrobial Compounds
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Published on: September 8, 2021

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在A级Staphylococcus aureus中P94位置的氨基酸变体调节基质结合和酶活性

Noah Cox-Tigre, Mia E Stewart, Jackson Tucker

    bioRxiv : the preprint server for biology
    |February 6, 2026
    PubMed
    概括

    研究人员探索了类酶A突变,以改善潜在抗生素开发的蛋白质结合. 葡萄球菌黄金菌分类酶A (saSrtA) 的新P94变体显示出增强的活性和基质特异性,表现优于现有的工程酶.

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