抑制TLR7通过破坏依赖ITGAM的免疫内皮细胞相互作用来限制心脏缺血损伤

概括

收费类受体7 (TLR7) 在缺血-再输液损伤后驱动炎症和心脏损伤. 在小鼠中,用恩帕托兰抑制TLR7可减少心肌损伤和改善心脏功能,为心脏病发作提供潜在的治疗方法.

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