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Updated: Feb 7, 2026

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激活KCC2可以扭转雌性雷特小鼠的神经生理和行为缺陷

Muhammad Nauman Arshad, Shu Fun Josephine Ng, Seda Salar

    bioRxiv : the preprint server for biology
    |February 6, 2026
    PubMed
    概括

    激活KCC2 (SLC12A5) 与OV350在雷特综合征小鼠模型中改善了运动协调,社交性和减少了发作. 这表明KCC2激活可以治疗神经发育障碍.

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