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Updated: Feb 7, 2026

Genome-wide Analysis of HDAC Inhibitor-mediated Modulation of microRNAs and mRNAs in B Cells Induced to Undergo Class-switch DNA Recombination and Plasma Cell Differentiation
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Genome-wide Analysis of HDAC Inhibitor-mediated Modulation of microRNAs and mRNAs in B Cells Induced to Undergo Class-switch DNA Recombination and Plasma Cell Differentiation

Published on: September 20, 2017

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PRDX6通过对抗由HDAC抑制剂诱导的铁死来调节免疫检查点抑制剂反应

Zeyu Liu, Jessy John, Nickolas Johnson

    bioRxiv : the preprint server for biology
    |February 6, 2026
    PubMed
    概括

    氧化素6 (PRDX6) 通过抑制铁亡,驱动对癌症疗法的耐药性,如HDAC抑制剂. 向PRDX6可以增强癌细胞死亡,并提高免疫治疗的有效性.

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