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Elements and Compounds01:27

Elements and Compounds

105.0K
Pure substances consist of only one type of matter. A pure substance can be an element or a compound. An element consists of only one type of atom, while a compound consists of two or more types of atoms held together by a chemical bond.
Elements
Elements are classified as atomic or molecular based on the nature of their basic units. They are unique forms of matter with specific chemical and physical properties that cannot break down into smaller substances by ordinary chemical reactions. There...
105.0K
Periodic Classification of the Elements04:00

Periodic Classification of the Elements

59.2K
The periodic table arranges atoms based on increasing atomic number so that elements with the same chemical properties recur periodically. When their electron configurations are added to the table, a periodic recurrence of similar electron configurations in the outer shells of these elements is observed. Because they are in the outer shells of an atom, valence electrons play the most important role in chemical reactions. The outer electrons have the highest energy of the electrons in an atom...
59.2K
Genomics02:02

Genomics

40.8K
Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
40.8K
Classification of Elements and Compounds02:54

Classification of Elements and Compounds

73.2K
Pure substances consist of only one type of matter. A pure substance can be an element or a compound. An element consists of only one type of atom, while a compound consists of two or more types of atoms held together by a chemical bond. Elements are classified as atomic or molecular based on the nature of their basic units.
Compounds are pure substances composed of two or more elements in fixed, definite proportions. Compounds are classified as ionic or molecular (covalent) based on the bonds...
73.2K
Key Elements for Plant Nutrition02:35

Key Elements for Plant Nutrition

24.3K
Like all living organisms, plants require organic and inorganic nutrients to survive, reproduce, grow and maintain homeostasis. To identify nutrients that are essential for plant functioning, researchers have leveraged a technique called hydroponics. In hydroponic culture systems, plants are grown—without soil—in water-based solutions containing nutrients. At least 17 nutrients have been identified as essential elements required by plants. Plants acquire these elements from the...
24.3K
Elements: Chemical Symbols and Isotopes02:31

Elements: Chemical Symbols and Isotopes

126.4K
A chemical symbol is an abbreviation used to indicate an element or an atom of an element. For example, the symbol for mercury is Hg. The same symbol is used to indicate one atom of mercury (microscopic domain) or to label a container of many atoms of the element mercury (macroscopic domain).
Some symbols are derived from the common English name of the element; others are abbreviations of the name in another language — Latin, Greek or German. For example, the symbol for aluminum (common name)...
126.4K

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Updated: Feb 7, 2026

Hi-C: A Method to Study the Three-dimensional Architecture of Genomes.
22:27

Hi-C: A Method to Study the Three-dimensional Architecture of Genomes.

Published on: May 6, 2010

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多态3D基因组架构由可转移元素介导.

Harsh Shukla, Yuheng Huang, Yi Zita Gao

    bioRxiv : the preprint server for biology
    |February 6, 2026
    PubMed
    概括
    此摘要是机器生成的。

    可转移元素 (TEs) 通过与周边中心基因组异性色素 (PCH) 相互作用,引入3D基因组结构变异. 这种多态性影响基因表达和进化,由像H3K9me3.3这样的表观遗传标记驱动.

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    Determination of the Optimal Chromosomal Locations for a DNA Element in Escherichia coli Using a Novel Transposon-mediated Approach
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    相关实验视频

    Last Updated: Feb 7, 2026

    Hi-C: A Method to Study the Three-dimensional Architecture of Genomes.
    22:27

    Hi-C: A Method to Study the Three-dimensional Architecture of Genomes.

    Published on: May 6, 2010

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    Genotyping Single Nucleotide Polymorphisms in the Mitochondrial Genome by Pyrosequencing
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    Genotyping Single Nucleotide Polymorphisms in the Mitochondrial Genome by Pyrosequencing

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    Determination of the Optimal Chromosomal Locations for a DNA Element in Escherichia coli Using a Novel Transposon-mediated Approach
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    Determination of the Optimal Chromosomal Locations for a DNA Element in Escherichia coli Using a Novel Transposon-mediated Approach

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    科学领域:

    • 基因组学就是基因组学.
    • 表观遗传学 在表观遗传学中,表观遗传学是指表观遗传学.
    • 进化生物学 进化生物学

    背景情况:

    • 三维 (3D) 基因组折叠对于基因调节至关重要.
    • 3D基因组结构的个体变异及其功能/进化影响尚不清楚.
    • 可转移元素 (TE) 是基因组变异的来源,并且可以与周周中心基异性色素 (PCH) 相互作用.

    研究的目的:

    • 调查多态TE插入是否会导致3D基因组结构的变化.
    • 探索TE-PCH相互作用在塑造基因组组织和功能中的作用.
    • 了解TE介导的3D基因组组织的进化影响.

    主要方法:

    • 深度覆盖的Hi-C测序在两个野生类型的Drosophila菌株中.
    • 开发一个Hi-C分析框架,用于与PCH进行空间相互作用的等位体比较.
    • 分析TE存在/不存在的多态性及其与PCH近距离的关联.

    主要成果:

    • 几乎40%的菌株特异性 euchromatic TEs 促进了与没有 TE 的等位基因相比更接近 PCH 的空间接近.
    • TE-PCH相互作用通过H3K9me3丰富,一种基于染色素的机制进行介导.
    • 无论是中心粒附近和端粒附近的TE都能增强PCH相互作用,影响相邻的基因表达.

    结论:

    • 通过与PCH相互作用,TEs有助于多态3D基因组组织.
    • 这种TE驱动的结构变异影响了基因组功能 (基因表达) 和进化.
    • 参与PCH相互作用的TE在进化上是年轻的,这表明对它们的选择.