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Updated: Feb 7, 2026

Tumor Transplantation for Assessing the Dynamics of Tumor-Infiltrating CD8+ T Cells in Mice
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Tumor Transplantation for Assessing the Dynamics of Tumor-Infiltrating CD8+ T Cells in Mice

Published on: June 12, 2021

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TCF1lo CD8 T细胞在瘤中自主繁殖和持续存在

Megan M Erwin, Natalie R Favret, Claudia N McDavid

    bioRxiv : the preprint server for biology
    |February 6, 2026
    PubMed
    概括

    缺少TCF1表达的瘤特异性CD8T细胞 (TST) 可以在瘤中繁殖并长期存在. 这一发现挑战了现有的范式,并强调TCF1-低TST对于抗癌免疫是至关重要的.

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