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通过 nociceptors 重编程单细胞阻碍了T细胞介导的瘤免疫力

Pavel Hanč, Adrian Blair, Harold R Neely

    bioRxiv : the preprint server for biology
    |February 6, 2026
    PubMed
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    被称为 nociceptors 的神经细胞通过将单细胞转化为髓质衍生抑制细胞 (MDSCs) 来促进膀癌中的免疫抑制. 阻断 nociceptors 增强T细胞介导的瘤排斥,提供了一个新的治疗策略.

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