相关实验视频

Updated: Feb 7, 2026

Methods for Evaluating the Role of c-Fos and Dusp1 in Oncogene Dependence
10:09

Methods for Evaluating the Role of c-Fos and Dusp1 in Oncogene Dependence

Published on: January 7, 2019

8.7K

在癌基因驱动的肺癌中,MTAP损失的患病率和可操作性

Takashi Sakai, Zofia Piotrowska, Charlotte I Wang

    bioRxiv : the preprint server for biology
    |February 6, 2026
    PubMed
    概括

    甲基氨酸酸酶 (MTAP) 损失在非小细胞肺癌 (NSCLC) 中很常见,表明对PRMT5抑制剂的脆弱性. 将PRMT5抑制剂与TKIs结合起来,对治疗晚期NSCLC有很大的前景.

    更多相关视频

    Detection of Targetable Alterations in Non-small Cell Lung Cancer using Next-generation Sequencing05:17

    Detection of Targetable Alterations in Non-small Cell Lung Cancer using Next-generation Sequencing

    Published on: October 10, 2025

    417
    Instillation and Fixation Methods Useful in Mouse Lung Cancer Research06:57

    Instillation and Fixation Methods Useful in Mouse Lung Cancer Research

    Published on: August 31, 2015

    29.6K

    相关概念视频

    Cancer-Critical Genes I: Proto-oncogenes01:33

    Cancer-Critical Genes I: Proto-oncogenes

    Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
    When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
    Such genes that act...
    11.5K
    Prevalence and Incidence01:08

    Prevalence and Incidence

    In statistical epidemiology and health sciences, two essential metrics—prevalence and incidence—are fundamental for understanding disease dynamics within a population. These measures enable public health officials, epidemiologists, and researchers to assess the burden of diseases, allocate resources effectively, and design impactful public health policies and interventions.
    Prevalence indicates the proportion of individuals in a population who have a specific disease or health...
    1.9K
    Line Loss01:10

    Line Loss

    The different configurations of source-load connections include wye (star) and delta connections. The relationship between line and phase voltages and currents varies depending on the configuration. When the source is supplying power, it is transmitted through the wires to the load, and during this transmission, some power is absorbed by the wires, leading to line loss.
    Line loss impacts power delivery efficiency in a balanced three-phase circuit. The symmetry in such a circuit simplifies the...
    545
    Fixed Action Patterns01:06

    Fixed Action Patterns

    A fixed action pattern (FAP) is a specific, hard-wired sequence of behaviors that occurs in response to an external stimulus, called a sign stimulus. The behavior is “fixed” because it is essentially unchangeable—proceeding similarly across individuals of a species every time it occurs.
    17.7K
    Reducing Line Loss01:18

    Reducing Line Loss

    In a three-phase circuit, line loss is an indicator of energy dissipated as heat due to the resistance of transmission lines. To address this, incorporating transformers into the system—a step-up transformer at the source and a step-down transformer at the load—is a strategic solution. Two three-phase transformers are introduced to improve this.
    With a step-up transformer at the source, the voltage is increased, thereby reducing the current in the transmission lines since power loss in...
    390
    Lung Capacity01:47

    Lung Capacity

    The air in the lungs is measured in volumes and capacities. Lung volume measures reflect the amount of air taken in, released, or left over after a lung function, like a single inhalation. Lung capacity measures are sums of two or more lung volume measures.
    56.4K