一个甲基组衍生的m6 -dAMP触发器组装了一个PUA-Cal-HAD免疫丝,耗尽dNTPs来中止菌体感染

概括

细菌通过感知改性核酸来防御菌体. 一个PUA-Calcineurin-CE-HAD模块形成细丝,耗尽dNTPs,停止菌体复制并触发流产性感染.

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