相关实验视频

Updated: Feb 7, 2026

Use of the Protease Fluorescent Detection Kit to Determine Protease Activity
09:00

Use of the Protease Fluorescent Detection Kit to Determine Protease Activity

Published on: August 4, 2009

28.9K

编程T细胞用于早期癌症检测,使用定制的蛋白酶可激活受体

Hathaichanok Phuengkham, Ying Chen, Anirudh Sivakumar

    bioRxiv : the preprint server for biology
    |February 6, 2026
    PubMed
    概括

    在OncoSCOUT中,使用具有蛋白酶可激活受体 (PAR) 的工程T细胞进行敏感的早期癌症检测. 这种新的策略通过在尿液中释放合成生物标志物来检测小瘤,其性能优于目前的方法.

    更多相关视频

    Detection of Protease Activity by Fluorescent Peptide Zymography09:56

    Detection of Protease Activity by Fluorescent Peptide Zymography

    Published on: January 20, 2019

    13.6K
    Applying an eMASS Customization Program as a Research Tool to Evaluate Consumer Benefits08:27

    Applying an eMASS Customization Program as a Research Tool to Evaluate Consumer Benefits

    Published on: September 27, 2019

    7.3K

    相关概念视频

    Types of Receptors: Cell Surface Receptors01:28

    Types of Receptors: Cell Surface Receptors

    Cell-surface receptors, also known as transmembrane receptors, are cell surface, membrane-anchored (integral) proteins that bind to external ligand molecules. This type of receptor spans the plasma membrane and performs signal transduction, converting an extracellular signal into an intracellular signal. Ligands that interact with cell-surface receptors do not have to enter the cell that they affect. Cell-surface receptors are also called cell-specific proteins or markers because they are...
    27.5K
    Internal Receptors01:31

    Internal Receptors

    Many cellular signals are hydrophilic and therefore cannot pass through the plasma membrane. However, small or hydrophobic signaling molecules can cross the hydrophobic core of the plasma membrane and bind to internal, or intracellular, receptors that reside within the cell. Many mammalian steroid hormones use this mechanism of cell signaling, as does nitric oxide (NO) gas.
    74.7K
    Receptor-mediated Endocytosis01:39

    Receptor-mediated Endocytosis

    Overview
    111.0K
    Enzyme-linked Receptors01:00

    Enzyme-linked Receptors

    Enzyme-linked receptors are proteins that act as both receptor and enzyme, activating multiple intracellular signals. This is a large group of receptors that include the receptor tyrosine kinase (RTK) family. Many growth factors and hormones bind to and activate the RTKs.
    Neurotrophin (NT) receptors are a family of RTKs, including trkA, trkB, and trkC (tropomyosin-related kinase) receptors. TrkA is specific for nerve growth factor (NGF), neurotrophin-6, and neurotrophin-7. TrkB binds...
    86.7K
    G-protein Coupled Receptors01:21

    G-protein Coupled Receptors

    G-protein coupled receptors are ligand binding receptors that indirectly affect changes in the cell. The actual receptor is a single polypeptide that transverses the cell membrane seven times creating intracellular and extracellular loops. The extracellular loops create a ligand specific pocket which binds to neurotransmitters or hormones. The intracellular loops holds onto the G-protein.
    132.1K
    Types of Receptors: Internal Receptors01:07

    Types of Receptors: Internal Receptors

    Many cellular signals are hydrophilic and cannot pass through the plasma membrane. However, small or hydrophobic signaling molecules can cross the hydrophobic core of the plasma membrane and bind intracellular receptors that reside within the cell cytoplasm or nucleus. Many mammalian steroid hormones and nitric oxide (NO) gas use this cell signaling mechanism.
    Similar to membrane-bound receptors, the binding of a ligand to the intracellular receptor of causes a conformational change in the...
    32.7K