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Updated: Feb 7, 2026

Efficient Transfection of In vitro Transcribed mRNA in Cultured Cells Using Peptide-Poloxamine Nanoparticles
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由AF4-SAXS揭示的mRNA-LNP亚群中的结构异质性:对货物加载和细胞转染的影响

Adrian Sanchez-Fernandez, Keira A Donnelly, Hans Bolinsson

    bioRxiv : the preprint server for biology
    |February 6, 2026
    PubMed
    概括

    脂质纳米粒子 (LNP) 显示了影响核酸输送的多种结构. 较高的mRNA负载 (N/P=6) 创建了统一的核心,改善了合理的LNP设计的转染效率.

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