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Updated: Feb 7, 2026

Investigating Protein Sequence-structure-dynamics Relationships with Bio3D-web
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超越本源序列恢复:改善了蛋白质结构的序列能量格局的建模

Foster Birnbaum, Amy E Keating

    bioRxiv : the preprint server for biology
    |February 6, 2026
    PubMed
    概括

    在蛋白质设计中优化机器学习模型以实现本机序列恢复 (NSR) 是不够的. 像PottsMPNN这样的新方法通过专注于折叠兼容性来改善序列生成和能量预测,而不仅仅是NSR.

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