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Updated: Feb 7, 2026

Rab10 Phosphorylation Detection by LRRK2 Activity Using SDS-PAGE with a Phosphate-binding Tag
08:55

Rab10 Phosphorylation Detection by LRRK2 Activity Using SDS-PAGE with a Phosphate-binding Tag

Published on: December 14, 2017

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LRRK2通过其脂质感应ALPS2动机内的酸化来调节ArfGAP1膜局部化,活性和神经元毒性

Md Shariful Islam, Valentin Cóppola-Segovia, Alessandra Musso

    bioRxiv : the preprint server for biology
    |February 6, 2026
    PubMed
    概括

    富含白的重复激酶2 (LRRK2) 酸化ArfGAP1会影响其功能和毒性. 调节这种相互作用可能为帕金森病提供治疗点.

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