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相关概念视频

RNA Structure01:23

RNA Structure

79.2K
Overview
The basic structure of RNA consists of a five-carbon sugar and one of four nitrogenous bases. Although most RNA is single-stranded, it can form complex secondary and tertiary structures. Such structures play essential roles in the regulation of transcription and translation.
Different Types of RNA Have the Same Basic Structure
There are three main types of ribonucleic acid (RNA): messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA). All three RNA types consist of a...
79.2K
RNA Structure01:19

RNA Structure

7.6K
The basic structure of RNA consists of a string of ribonucleotides attached by phosphodiester bonds. Although most RNA is single-stranded, it can form complex secondary and tertiary structures. Such structures play essential roles in the regulation of transcription and translation.
Different Types of RNA Have the Same Basic Structure
There are three main types of ribonucleic acid (RNA) involved in protein synthesis: messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA). All three...
7.6K
Translation01:31

Translation

156.8K
Lesson: Translation
Translation is the process of synthesizing proteins from the genetic information carried by messenger RNA (mRNA). Following transcription, it constitutes the final step in the expression of genes. This process is carried out by ribosomes, complexes of protein and specialized RNA molecules. Ribosomes, transfer RNA (tRNA), and other proteins produce a chain of amino acids—the polypeptide—as the end product of translation.
Translation Produces the Building Blocks of...
156.8K
Coordination Number and Geometry02:57

Coordination Number and Geometry

19.0K
For transition metal complexes, the coordination number determines the geometry around the central metal ion. Table 1 compares coordination numbers to molecular geometry. The most common structures of the complexes in coordination compounds are octahedral, tetrahedral, and square planar.
19.0K
Termination of Translation01:44

Termination of Translation

27.7K
The large ribosomal subunit has several important structures essential to translation. These include the peptidyl transferase center (PTC) - which is the site where the peptide bond is formed - and a large, internal, water-filled tube through which the nascent polypeptide moves. This latter structure is called the Peptide Exit Tunnel, and it begins at the PTC and spans the body of the large ribosomal subunit. During translation, as the nascent polypeptide chain is synthesized, it passes through...
27.7K
RNA Stability01:53

RNA Stability

35.8K
Intact DNA strands can be found in fossils, while scientists sometimes struggle to keep RNA intact under laboratory conditions. The structural variations between RNA and DNA underlie the differences in their stability and longevity. Because DNA is double-stranded, it is inherently more stable. The single-stranded structure of RNA is less stable but also more flexible and can form weak internal bonds. Additionally, most RNAs in the cell are relatively short, while DNA can be up to 250 million...
35.8K

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相关实验视频

Updated: Feb 7, 2026

Optical Tweezers to Study RNA-Protein Interactions in Translation Regulation
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Optical Tweezers to Study RNA-Protein Interactions in Translation Regulation

Published on: February 12, 2022

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RNA结构协调了整个微生物程序的翻译.

Hao Wu, Caini Zhou, Shoucheng Du

    bioRxiv : the preprint server for biology
    |February 6, 2026
    PubMed
    概括
    此摘要是机器生成的。

    细胞mRNA结构在酵母半转化过程中动态调节翻译. RNA螺旋酶协调这些结构,当转录有限时影响蛋白质生产和介质进展.

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    Structure and Coordination Determination of Peptide-metal Complexes Using 1D and 2D 1H NMR
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    Structure and Coordination Determination of Peptide-metal Complexes Using 1D and 2D 1H NMR

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    Defining the Program of Maternal mRNA Translation during In vitro Maturation using a Single Oocyte Reporter Assay
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    相关实验视频

    Last Updated: Feb 7, 2026

    Optical Tweezers to Study RNA-Protein Interactions in Translation Regulation
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    Optical Tweezers to Study RNA-Protein Interactions in Translation Regulation

    Published on: February 12, 2022

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    Structure and Coordination Determination of Peptide-metal Complexes Using 1D and 2D 1H NMR
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    Structure and Coordination Determination of Peptide-metal Complexes Using 1D and 2D 1H NMR

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    Defining the Program of Maternal mRNA Translation during In vitro Maturation using a Single Oocyte Reporter Assay
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    Defining the Program of Maternal mRNA Translation during In vitro Maturation using a Single Oocyte Reporter Assay

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    科学领域:

    • 分子生物学分子生物学
    • 遗传学 遗传学 是一个
    • 细胞生物学 细胞生物学

    背景情况:

    • 虽然mRNA结构会影响翻译效率,但它在化等复杂过程中的作用尚不清楚.
    • 酵母半转化为研究因转录有限而导致的动态转录后调节提供了一个独特的模型.

    研究的目的:

    • 调查mRNA结构在酵母半转化过程中协调翻译中的作用.
    • 了解RNA螺旋酶如何调节mRNA结构和翻译控制.

    主要方法:

    • 在酵母半变异过程中,在多个时间点上对mRNA结构 (结构体) 的高分辨率分析.
    • 对2000多个注释的mRNA的mRNA结构的量化.
    • 分析RNA螺旋酶 (Ded1p) 水平及其对mRNA结构和翻译的影响.

    主要成果:

    • 梅奥特语录通常表现出灵活的结构,增强了翻译.
    • 复杂的mRNA结构通过减少核糖体流量和促进替代启动来阻碍翻译.
    • 基于RNA结构的RNA酶水平的动态振荡重新编程了基于RNA结构的细胞范围的翻译偏好.
    • 破坏特定的mRNA结构或螺旋酶水平会损害介质蛋白质稳定和进展.

    结论:

    • 毫米RNA结构和RNA螺旋酶的协同作用在半转化过程中协调了细胞范围的翻译动态.
    • 这突显了一个关键的转录后调节机制,当转录受到染色体凝聚的限制时,它就会活跃起来.
    • 这些发现揭示了一个复杂的基因表达控制层,这对于成功的半变化至关重要.