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Updated: Feb 7, 2026

Real-Time Monitoring of Aurora kinase A Activation using Conformational FRET Biosensors in Live Cells
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针对性治疗诱导的染色体不稳定性决定了对光激酶A的线粒性依赖

Chendi Li, Varuna Nangia, Melissa D Vieira

    bioRxiv : the preprint server for biology
    |February 6, 2026
    PubMed
    概括

    克拉斯抑制导致克拉斯突变肺癌的染色体不稳定性 (CIN). 结合KRAS和光激酶A抑制剂显示了治疗协同作用,CIN预测了治疗反应.

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