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Updated: Feb 7, 2026

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抑制PU.1使干单细胞AML对BCL2阻塞敏感

William M Yashar, Itallia V Pacentine, Akram Taherinasab

    bioRxiv : the preprint server for biology
    |February 6, 2026
    PubMed
    概括

    急性髓性白血病 (AML) 亚型对venetoclax.表现出不同的反应. 一种新的干细胞单细胞AML亚型具有耐药性,但结合PU.1和BCL2抑制可能会改善治疗结果.

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