使用受控兴奋剂治疗可卡因使用障碍在注意力缺陷/多动障碍的设置:一个案例研究
Mack Bozman1, Brent Collier1, Aniket Malhotra1
1Department of Psychiatry and Behavioral Neurobiology, University of Alabama at Birmingham, Birmingham, AL, United States.
Frontiers in psychiatry
|February 6, 2026
概括
这项案例研究表明,德克斯特罗胺-胺盐可能有助于可卡因使用障碍 (CUD) 和注意力缺陷/多动症障碍 (ADHD) 患者的戒断. 这种精神兴奋剂治疗显示出作为这种患者子组的降低危害策略的前景.
科学领域:
- 精神病学是一个精神病学.
- 成 药物 药物 药物 药物
- 药理学 药理学是指药理学的学科.
背景情况:
- 可卡因使用障碍 (CUD) 存在重大治疗挑战,缺乏FDA批准的药物.
- 应急管理 (CM) 是有效的,但由于实际障碍而未得到充分利用.
- 非标签性精神兴奋剂的使用正在探索CUD,特别是在并发症的注意力缺陷/多动性障碍 (ADHD).
研究的目的:
- 介绍一项关于精神刺激疗法在患有CUD和ADHD的患者中疗效的案例研究.
- 探索兴奋剂替代作为降低危害策略的潜力.
主要方法:
- 一个中年男性的病例报告,有ADHD病史和最近的CUD.
- 恢复使用德克斯特罗安非他胺-安非他胺盐进行治疗.
- 通过尿液药物查和可卡因嗜好量表 (CCS) 监测可卡因戒断.
主要成果:
- 患者实现了持续的可卡因戒断超过六个月,这是他最长的缓解期.
- 阴性尿液药物查和降低的渴望得分 (CCS) 支持清醒.
- 这种治疗被认为是一种成功的减伤策略.
结论:
- 精神兴奋剂治疗,特别是德克斯特罗安非他-安非他盐,可能是选择性CUD和同时出现ADHD的患者的可行降害方法.
- 鉴于过量使用率的上升,对兴奋剂使用障碍的个性化治疗方法的进一步研究至关重要.
- 这一案例支持了越来越多的证据,证明刺激剂替代疗法可用于管理CUD.
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