估计老年人身体弹性方法的方法方法方法:在两个临床环境中进行比较
Jan J Duin1,2, Rosalinde A L Smits1,2, Tim Krans1,2
1Department of Internal Medicine, Section Gerontology and Geriatrics, Leiden University Medical Center, Leiden, South Holland, The Netherlands.
Age and ageing
|February 6, 2026
概括
测量老年人身体性的不同方法显示出缺乏一致性和对结果的预测价值有限. 高频度的纵向测量可以更好地捕捉临床实践中的弹性.
科学领域:
- 老年学是指老年学的学科.
- 临床医学 临床医学
- 卫生科学 卫生科学 卫生科学
背景情况:
- 现有的评估老年人身体性的方法,包括表型,预期恢复和适应衰老方法,缺乏明确的比较性能数据.
- 这项研究旨在评估在两个不同的临床环境中这些不同的身体弹性方法的协议和预测能力.
研究的目的:
- 为了比较三个不同的物理弹性评估方法之间的协议:表型,预期恢复和适应衰老.
- 评估这些方法对12个月死亡率和功能衰退,生活质量下降或死亡率的复合终点的预测性表现.
- 评估这些弹性措施的附加预后价值,超出了基本的临床预测因素.
主要方法:
- 三种方法方法 (表型,预期恢复,适应衰老) 应用于两个队列:接受化疗的老年人 (TENT) 和急诊部急性疾病患者 (APOP).
- 使用卡茨日常生活活动和劳顿日常生活仪器活动尺度来测量身体功能.
- 使用Cohen的kappa评估了协议,并使用曲线下的面积 (AUC) 评估了预测性表现.
主要成果:
- 物理弹性方法之间的一致性不好到中等 (κ = -0.10到0.64).
- 所有方法在12个月死亡率 (AUC0.55-0.69) 和复合结果 (AUC0.52-0.66) 上都只显示出适度的区分能力.
- 物理弹性方法提供了有限的额外预测价值,超出了后续功能评分和年龄等简单预测因素.
结论:
- 评估的身体弹性方法确定了不同患者群体的弹性,并显示出有限的预后价值.
- 当前的方法可能无法充分捕捉物理弹性的动态性质.
- 建议进行更高频度的纵向测量,以更好地量化临床环境中的身体弹性.
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