对于患有性结肠炎的成年人来说,疾病过程中的营养需求:系统的范围审查
Samantha Plush1,2,3, Robert V Bryant1,2,3, Rachel H Davis1,2,3
1Department of Gastroenterology and Hepatology, The Queen Elizabeth Hospital, Woodville South, Australia.
Critical reviews in food science and nutrition
|February 6, 2026
概括
性结肠炎 (UC) 的营养需求尚不清楚,尤其是在缓解期或轻度至中度疾病期间. 目前的证据表明,只有在急性严重UC时才需要更高的蛋白质,但对UC患者需要更多的研究.
科学领域:
- 胃肠病学和临床营养学
背景情况:
- 性结肠炎 (UC) 是结肠的慢性炎症状况.
- 对于UC的营养需求通常是从克罗恩病 (CD) 数据推断出来的.
- UC和CD之间明显的生理差异可能需要独特的营养建议.
研究的目的:
- 进行范围审查,评估UC的成年患者的营养需求.
- 为了确定根据疾病活动分层的营养需求.
主要方法:
- 在范围审查中采用了一种系统搜索策略,数据提取到2025年6月.
- 包括21项研究,涉及617名成年人.
- 休息能量消耗 (mREE) 用间接热量计进行测量.
主要成果:
- mREE因疾病活动而异:静止UC (28.931.5 kcal/kg/d无脂肪质量),轻度至中度UC (26.4 kcal/kg/d),以及急性严重UC (ASUC) (23.9 kcal/kg/d).
- 历史数据显示,ASUC的蛋白质需求为1.21.4g/kg/天.
- 对于静止或轻中度UC的蛋白质需求,以及疾病状态的微量营养素需求,在很大程度上仍未确定.
结论:
- 目前的证据不足以确定UC患者的宏观和微量营养素需求.
- 根据较旧的研究,建议增加蛋白质摄入量以达到ASUC.
- 基于证据的UC营养指南需要进一步进行精心设计的,疾病活性分层的研究.
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