评估风险计算器对医生在IPMN监测中的风险感知和决策的影响:一项随机试验
Greg D Sacks1, Ida J Korfage2, James Farrell3
1Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, New York University Grossman School of Medicine, NYU-Langone Health, New York, NY, USA. greg.sacks@nyulangone.org.
Annals of surgical oncology
|February 6, 2026
概括
风险计算器 (RCs) 并没有显著改变临床医生的关于胰腺导管内皮质粘膜瘤 (IPMNs) 监测的决定. 临床医生改变建议的门差异很大,这表明需要进一步研究RC的有效性.
科学领域:
- 胃肠病学 胃肠病学
- 临床决策支持 临床决策支持
- 在瘤学瘤学.
背景情况:
- 胰腺导管内 papillary 粘膜瘤 (IPMNs) 需要监测以检测进展.
- 风险计算器 (RCs) 的目的是帮助临床医生停止对低风险IPMN的监测.
- RCs对IPMN管理临床判断的影响尚未完全理解.
研究的目的:
- 评估风险计算器对临床医生对IPMN进展风险的评估的影响.
- 确定RC是否影响继续对低风险IPMN监测的决定.
- 为了确定临床医生会改变其管理建议的癌症风险值.
主要方法:
- 临床医生审查了低风险IPMNs的细节,评估进展可能性和监测建议.
- 参与者被随机分配,只接受 vignettes 或 vignettes 补充DART-1风险计算器 (RC) 的数据.
- 在各组之间比较了判决,决定和个人风险门.
主要成果:
- 该RC没有显著改变临床医生对跨 vignettes 的IPMN进展的感知可能性.
- 在各组之间继续监测的建议中没有发现显著差异.
- 临床医生在报告的癌症风险值中表现出广泛的范围,以改变管理.
结论:
- 研究的RC没有显著影响临床医生的风险感知或IPMNs的监测决策.
- 这项研究受到小样本规模的限制,因此需要谨慎解释.
- 临床医生的风险值存在显著的变化,需要进一步的研究来了解为什么RCs可能不会影响决策.
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