在癌症幸存者中进行乳腺癌查:系统性审查和元分析
Sanjeev Bista1, Hannah Harsanyi2, Momtafin Khan3
1University of Calgary Calgary Canada.
概括
女性癌症幸存者显示乳腺癌查率高于没有癌症的个体,但整体率仍低于目标. 需要进一步的研究,以提高这一群体的查遵守率.
科学领域:
- 在瘤学瘤学.
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 癌症幸存者面临患上后续癌症的风险较高,包括乳腺癌.
- 了解这一群体的乳腺癌查行为对于早期检测和改善结果至关重要.
研究的目的:
- 系统地审查和量化乳腺癌查在女性癌症幸存者 (不包括乳腺癌幸存者) 的患病率.
- 为了比较癌症幸存者和无癌症对照者之间乳腺癌查吸收的可能性.
主要方法:
- 系统的文献综述和随机效应的元分析.
- 包括62项研究来量化查流行率,并比较幸存者与对照者的查概率.
- 在主要癌症部位进行的分层分析.
主要成果:
- 在女性癌症幸存者中,乳腺癌查的总体患病率为0.67 (95% CI:0.62,0.71).
- 患病率因原发性癌症部位而异 (肺部为0.49,子宫为0.75),在使用自我报告并在北美进行的研究中更高.
- 与没有癌症的对照人群相比,癌症幸存者接受乳腺癌查的几率明显更高 (OR: 1.24,95% CI: 1.13-1.36).
结论:
- 癌症幸存者比无癌症患者的乳腺癌查率更高,但这些率远远低于既定的人口目标.
- 需要有针对性的干预措施来解决查不遵守问题,并加强癌症幸存者的参与,因为他们患乳腺癌的风险增加.
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