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一种混合前贝叶斯方法,用于在全球药物开发中结合国内真实世界数据和海外数据

Keer Chen1, Zengyue Zheng1, Pengfei Zhu2

  • 1Department of Biostatistics, School of Public Health, Southern Medical University, Guangzhou, China.

Statistical methods in medical research
|February 6, 2026
PubMed
概括

一个新的混合贝叶斯框架,EQPS Robust MAP (rMAP),通过整合真实世界数据 (RWD) 和解决数据异质性和偏差,提高临床试验效率. 这种方法提高了复杂的试验设计的证据可靠性.

关键词:
贝叶斯语 贝叶斯语 贝叶斯语 贝叶斯语混合临床试验的设计.外部试验数据 外部试验数据进行元分析的方法.倾向性得分是指倾向性得分.现实世界的数据数据.

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