在人体内对抗癌症的效果的Artemisia sieberi在人类乳腺癌细胞:一个系统的审查
Fatimah G Albani1,2,3, Entissar S Alsuhaibani2, Sahar S Alghamdi3,4,5
1Department of Biology, College of Science, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia.
Journal of evidence-based integrative medicine
|February 6, 2026
概括
药用灌木Artemisia sieberi在初步实验室研究中显示出潜在的抗乳腺癌作用. 需要进一步的研究来探索其在各种乳腺癌类型的疗效,包括三阴性乳腺癌.
科学领域:
- 植物化学 植物化学
- 药理学 药理学是指药理学的学科.
- 在瘤学瘤学.
背景情况:
- 石 (Artemisia sieberi) 是一种药用灌木,含有许多具有抗癌性质的化合物.
- 之前的研究表明,A. sieberi在包括乳腺癌在内的各种癌症类型中具有潜在的抗癌活性.
研究的目的:
- 系统地审查体外证据,对Artemisia sieberi提取物的抗乳腺癌活性.
- 评估A. sieberi对特定乳腺癌细胞系,即MCF-7和MDA-MB-231的影响.
主要方法:
- 从创立到2024年,在主要的科学数据库 (PubMed,ScienceDirect,Scopus,Web of Science,Google Scholar) 中进行了系统的文献搜索.
- 在选择和审查研究时,遵循了PRISMA指南和Cochrane手册.
- 在包括在体外研究中的偏差风险评估中使用了QUIN工具.
主要成果:
- 审查中包括了六项体外研究.
- 阿尔特米西亚西贝里提取物通过诱导亡,抑制细胞生长和基因表达调节等机制显示出潜在的抗乳腺癌作用.
- 审查的研究表明,A. sieberi对乳腺癌细胞系的初步体外抗癌活性.
结论:
- 阿尔特米西亚西贝里在体外显示出有前途的抗乳腺癌潜力.
- 需要进一步的研究来调查各种A. sieberi提取物与各种乳腺癌细胞系,包括治疗耐药的类型,如三阴性乳腺癌 (TNBC).
- 未来的研究应该扩展到体内和临床研究,以验证这些初步发现.
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