在斯里兰卡量化家庭液体药物剂量错误:一种隐藏的公共卫生风险
Manori Jayasinghe1, Hasiduni Madhushika1, Kanchana Wijesekera1
1Department of Pharmacy, Faculty of Allied Health Sciences, University of Ruhuna, Galle, Sri Lanka.
PLOS global public health
|February 6, 2026
概括
斯里兰卡的家庭药物测量工具往往不准确,导致潜在的剂量错误. 标准化设备和用户教育对于低资源环境中的患者安全至关重要.
科学领域:
- 药理学 药理学是指药理学的学科.
- 公共卫生 公共卫生
- 医疗器械 医疗器械
背景情况:
- 液体药物的不准确测量是一个重要的患者安全问题,特别是在资源较少的环境中.
- 尽管斯里兰卡采用了米制,但子等家用测量工具仍被广泛用于药物剂量.
- 大量分发和非正式的剂量说明加剧了这个问题.
研究的目的:
- 评估斯里兰卡常用的家庭液体药物测量工具的体积精度.
- 确定这些工具对药物剂量错误的潜在贡献.
- 突出监管行动和改进实践的需要.
主要方法:
- 在斯里兰卡加勒区卡拉皮蒂亚的50个家庭进行了横截面调查.
- 使用验证的称重和体积测量方法测试经常使用的测量设备.
- 根据美国药典 (USP) 规格对准确性的评估.
主要成果:
- 在所有卷中,只有53.4%的测量杯符合USP准确性标准.
- 86.2%的测量杯符合5.00毫升的标准,但62.5%的测量没有达到标准.
- 家庭茶匙和匙显示出显著的体积变化,超过93%的体积低于预期.
结论:
- 斯里兰卡常见的家庭用剂量工具的广泛不准确性对药物安全构成了可以避免的风险.
- 迫切需要采取监管行动,要求标准化,校准测量设备.
- 将用户教育整合到处方和发行实践中,对于患者安全至关重要.
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