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Updated: Feb 8, 2026

Screening and Identification of Small Peptides Targeting Fibroblast Growth Factor Receptor2 using a Phage Display Peptide Library
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Screening and Identification of Small Peptides Targeting Fibroblast Growth Factor Receptor2 using a Phage Display Peptide Library

Published on: September 30, 2019

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菌体显示的异酸介导循环化使得发现宏环结合剂成为可能

Liwen Bai1, Ting Dan2, Peng Cheng2

  • 1Shaanxi Key Laboratory of Natural Products & Chemical Biology, College of Chemistry & Pharmacy, Northwest A&F University, Yangling 712100, Shaanxi, PR China.

Science advances
|February 6, 2026
PubMed
概括

这项研究引入了一种新的pH调节的交叉链接器,用于循环菌素显示,增强支架多样性,并使有效的药物发现成为可能. 该方法成功地确定了关键治疗标的强有力的结合剂.

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Using Phage Display to Develop Ubiquitin Variant Modulators for E3 Ligases06:30

Using Phage Display to Develop Ubiquitin Variant Modulators for E3 Ligases

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