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Updated: Feb 8, 2026

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一种综合性NMR方法用于评估与单克隆抗体的链接器-有效载荷结合

Veronica Ghini1, Sofia Siciliano2, Leonardo Querci1

  • 1Department of Chemistry, University of Florence, via Della Lastruccia 3, 50019 Sesto Fiorentino, Florence, Italy.

Bioconjugate chemistry
|February 6, 2026
PubMed
概括

我们开发了一种新型的NMR方法,以表征抗体-药物合物 (ADC),而不会破坏它们. 这种技术提供了对抗体结构和药物有效载荷特性的洞察,推进了ADC分析.

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