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Updated: Feb 8, 2026

An ELISA Based Binding and Competition Method to Rapidly Determine Ligand-receptor Interactions
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An ELISA Based Binding and Competition Method to Rapidly Determine Ligand-receptor Interactions

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一个简化的工作流程,用于单克隆抗体的早期配方开发,包括多属性方法和带结合测定

Rachel Smith1, Colin Guy2, Rosie Upton2

  • 1Labcorp York, York Biotech Campus, York YO41 1LZ, UK.

Journal of pharmaceutical and biomedical analysis
|February 6, 2026
PubMed
概括

一个新的工作流简化了使用LC-MS MAM和SPR.的单克隆抗体 (mAb) 配方开发. 这种方法提高了效率,降低了成本,缩短了时间表,同时确保了关键的质量属性和患者安全.

关键词:
强制性降解强制性降解配方开发 配方开发液体染色学-质谱学-质谱学甲氨酸的氧化方式多属性方法多属性方法.这就是Pembrolizumab.

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