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Updated: Feb 8, 2026

In Vitro Assay for Studying the Aggregation of Tau Protein and Drug Screening
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在诱导性陶病症小鼠模型中,NRF2缺陷阻止了病态的Tau播种和传播

Yaiza López-Sampere1, Pol Mengod Soler1, Sergio Roca-Pereira1

  • 1Neurology and Neurogenetics Group - Neuroscience Program, Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, 08907, Spain; Network Centre of Biomedical Research of Neurodegenerative Diseases (CIBERNED), Institute of Health Carlos III, L'Hospitalet de Llobregat, Barcelona, 08907, Spain.

Redox biology
|February 6, 2026
PubMed
概括

在阿尔茨海默病的小鼠模型中,核因子红色素2相关因子2 (NRF2) 的损失令人惊地减少了的播种和传播. 这表明NRF2对的传播至关重要,可能是治疗点.

关键词:
衰老的衰老 衰老的衰老阿尔茨海默病的疾病阿尔茨海默病的疾病.这就是NRF2的NRF2.氧化应激是一种氧化应激.塔乌·塔乌 (Tau Tau) 是一个

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