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Updated: Feb 8, 2026

Phenotypic Analysis and Isolation of Murine Hematopoietic Stem Cells and Lineage-committed Progenitors
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与Ezh2的比较揭示了Jarid2在造血干细胞谱系中的PRC2依赖功能

Hassan Bjeije1, Wentao Han1, Shuyang Lin2

  • 1Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.

Stem cell reports
|February 6, 2026
PubMed
概括

贾里德2是一种多组复合抑制复合体2 (PRC2) 辅因子,主要限制了血液构造原始体的骨髓分化. 它的PRC2-依赖性功能对于正常的造血和防止骨髓系的过度生长至关重要.

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