在缓慢流动的血管形中,白素电硬化疗法和皮肤超色素化:一项回顾性单心分析
Julius Henry Loeser1, Dominik Schramm1, Beatrix Rita Cucuruz1
1University Hospital and Polyclinic for Radiology, University Hospital Halle, Halle (Saale), Germany.
概括
针对血管形的白素电硬化疗法 (BEST) 可能会导致皮肤多颜色,特别是在六角电极和较高剂量 (≥0.10 mg/kg) 的情况下. 选择电极和小心剂量是最大限度地减少这种副作用的关键.
科学领域:
- 血管外科 血管外科
- 皮肤病学 皮肤病学
- 干预性放射学 干预性放射学
背景情况:
- 硬化疗法是缓慢流动血管形的标准.
- 蓝素电硬化疗法 (BEST) 在治疗复发性病变方面表现有前途.
- 皮肤色素过高是BEST的一个已知的不良影响.
研究的目的:
- 分析发生情况和与BEST后皮肤多颜色化相关的因素.
- 为了将研究结果与关于白色素诱导的多发色素的现有文献进行比较.
主要方法:
- 在21个月内对72名患者 (80次手术) 进行了回顾性分析.
- 过色素的临床和摄影文档.
- 分析治疗参数,包括电极类型和白胺剂量 (mg/kg).
主要成果:
- 超色素发生在4/7的LMs,20/44的VMs和16/29的联合毒淋巴形.
- 与NFD和VGD相比,使用六角电极的发病率更高 (58.9%).
- 静脉注射后更频繁 (61.8%) 与内伤 (41.3%) 相比.
- 剂量值≥0.10 mg/kg的白色素增加了多颜色化风险 (RR 2.30).
结论:
- 在BEST后的皮肤多颜色变化很常见,并受到电极几何和剂量的影响.
- 六角电极和较高的白胺剂量 (≥0.10 mg/kg) 与风险增加有关.
- 精明的电极选择和剂量最小化可以改善化品的结果.
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