与复杂胃分裂相关的孕产妇风险因素:大麻暴露和反复的尿路感染可能是可修改的目标
Olugbenga Awolaran1, Kaitlyn MacGregor1, Suyin A Lum1
1Division of Pediatric Surgery, Departments of Surgery and Pediatrics & Child Health, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, and Children's Hospital Research Institute of Manitoba, Winnipeg, Manitoba, Canada.
Journal of pediatric surgery
|February 6, 2026
概括
暴露于大麻和怀孕期间反复出现的尿路感染与复杂的胃关联. 这些因素可能是可修改的,以减少严重的胃症并发症的风险.
科学领域:
- 围产期健康 围产期健康
- 有先天性异常.
- 母亲的风险因素 母亲的风险因素
背景情况:
- 胃分裂是一种先天性异常,具有已知的孕产妇风险因素.
- 导致复杂变异性胃症的诱导因素在很大程度上是未知的.
- 识别这些因素对于有针对性的干预至关重要.
研究的目的:
- 为了确定与复杂的胃分裂相关的孕产妇风险因素.
- 为了比较母亲的风险因子简单与复杂的胃分裂怀孕的概况.
- 为了告知严重胃的潜在预防策略.
主要方法:
- 追溯分析了194个胃病例 (1991-2022年).
- 根据肠道并发症,将病例分为"简单"或"复杂".
- 提取和统计分析母亲健康和生活方式数据.
主要成果:
- 大麻使用与复杂的胃关联 (调整后OR=2.64).
- 反复发生的尿路感染与复杂的胃 (RaR=3.78) 有着强烈的关联.
- 没有发现与吸烟,酒精,麻醉药物或盆腔炎症疾病有显著的关联.
结论:
- 孕期和孕期大麻暴露与复杂的胃关联.
- 经常出现的尿路感染与复杂形式的胃结有关.
- 这些已识别的因素可能是减少胃症并发症的可修改目标.
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