执行功能障碍与中风幸存者的轻度至重度上肢缺陷之间的关联:休息状态功能近红外光谱研究
Man Wang1, Lijun Zhang2, Cheng Xie2
1Department of Rehabilitation Medicine, Huashan Hospital, Fudan University, No. 12 Middle Wulumuqi Road, Jing'an District, Shanghai 200040, China; Department of Rehabilitation Medicine, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200233, China.
Behavioural brain research
|February 6, 2026
概括
执行功能与中风后的上肢缺陷有关,因损伤严重程度而有所不同. 在中风后的执行功能障碍患者中,大脑连接模式因运动缺陷而有所不同.
科学领域:
- 神经科学是一个神经科学.
- 康复医学 康复医学 康复医学
- 认知科学 认知科学
背景情况:
- 卒中幸存者经常经历上肢缺陷和执行功能障碍.
- 了解认知和运动障碍之间的关系对于有效的康复至关重要.
研究的目的:
- 检查中风幸存者的执行功能和上肢缺陷之间的关联.
- 通过功能近红外光谱学 (fNIRS) 对中风后执行障碍 (PSEI) 患者进行休息状态功能连接 (FC) 的研究.
主要方法:
- 评估了122名中风幸存者,他们有不同的上肢缺陷.
- 认知功能使用MoCA,FAB和Stroop测试进行评估.
- 用FMA-UE和ARAT测量运动功能;收集静止状态fNIRS数据.
主要成果:
- 执行功能缺陷与中风后上肢损伤的严重程度相关.
- 皮层和皮层下区域的功能连接模式在PSEI患者之间有所不同,具有不同的运动缺陷.
结论:
- 脑卒中后执行功能和上肢功能之间的联系取决于运动障碍的程度.
- 在PSEI患者中观察到大脑功能连接的改变,与上肢缺陷的严重程度有关.
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