健康学龄前儿童骨质定量超声波测量的纵向变化:母婴决定因素
Sandra Cerar1, Evgen Benedik2, Tatjana Robič Pikel3
1Department of Neonatology, University Children's Hospital, University Medical Centre Ljubljana, 1000, Ljubljana, Slovenia; Faculty of Medicine, University of Ljubljana, Vrazov trg 1, 1000, Ljubljana, Slovenia.
孕妇维生素D缺乏和怀孕期间的甲状腺问题,以及儿童的BMI,与学龄前儿童的骨密度较低有关. 这些因素影响了从婴儿期到7岁的骨头音速 (SOS) 发育.
科学领域:
- 儿科 儿科 儿科
- 整形外科 整形外科 整形外科
- 内分泌学 在内分泌学.
背景情况:
- 在生命早期,母亲的健康和环境因素显著影响后代的骨发育.
- 了解这些影响对于确定潜在的干预措施来促进从婴儿期到学龄前的最佳骨健康至关重要.
研究的目的:
- 调查孕妇在怀孕期间和童年环境因素对学龄前后代骨健康的影响.
- 为了确定与早期儿童骨矿物质密度相关的特定母婴因素.
主要方法:
- 一项前性队列研究监测了146对斯洛文尼亚的母婴,从出生到7岁.
- 孕产妇的数据包括健康状况,人体测量,25-氧维生素D (25(OH) D),阿迪波内克丁,饮食和骨超声波 (SOS).
- 后代的骨SOS在出生,1,3,12个月和7岁时被测量;饮食在7岁时被评估.
主要成果:
- 音速的骨速 (SOS) 值显示随着时间的推移发生了显著变化,在1-3个月后下降,并在12个月和7年后增加.
- 较低的母体25~OH) D度和母体甲状腺功能障碍与出生时后代SOS的较低程度有关.
- 在整个研究期间,儿童体重指数 (BMI) Z-score 与骨SOS值相关.
结论:
- 该研究发现,学龄前儿童的骨矿物质密度低于最佳.
- 低孕产妇25~OH) D,孕产妇甲状腺功能障碍,以及孩子的BMI Z-score是减少骨SOS的危险因素.
- 由于研究队列的健康生活方式,研究结果可能无法概括.
更多相关视频
10:57Determining Soil-transmitted Helminth Infection Status and Physical Fitness of School-aged Children
Published on: August 22, 2012
08:05Measuring Statistical Learning Across Modalities and Domains in School-Aged Children Via an Online Platform and Neuroimaging Techniques
Published on: June 30, 2020
相关概念视频
Longitudinal Research
Longitudinal Studies
pre-mRNA Processing
Once about 20-40 ribonucleotides have been joined together by RNA polymerase, a group of enzymes adds a “cap” to the 5’ end of the growing transcript. In this process, a 5’ phosphate is replaced by modified guanosine that has a methyl group attached to it (7-Methyl...
Pre-mRNA Processing: Modification of pre-mRNA Ends
Once about 20-40 ribonucleotides have been joined together by RNA polymerase, a group of enzymes adds a cap to the 5' end of the growing transcript. In this process, a 5' phosphate is replaced by modified guanosine that has a methyl group attached (7-methyl guanosine). This 5' cap helps...
Ultrasound II: Endoscopic Ultrasound and FibroScan
Endoscopic Ultrasound (EUS):
Determining Order of Reaction
