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Updated: Feb 8, 2026

Fully Processed Recombinant KRAS4b: Isolating and Characterizing the Farnesylated and Methylated Protein
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Published on: January 16, 2020

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KRAS4a和KRAS4b显示了RAS-RAF膜动态的明显的脂质依赖调节

Konstantia Georgouli1, Jeremy O B Tempkin1, Liam G Stanton2

  • 1Physical and Life Sciences (PLS) Directorate, Lawrence Livermore National Laboratory, Livermore, CA 94550.

The Journal of biological chemistry
|February 6, 2026
PubMed
概括

克拉斯4a和克拉斯4b蛋白与细胞膜有动态相互作用,受脂质组成的影响. 它们超变区的差异会影响这些相互作用,影响RAS介导的信号传输.

关键词:
在KRAS函数的KRAS函数中.这就是KRAS4a.这就是KRAS4bb.在 RAS-RBDCRD 膜动力学上.在RAS-膜生物学上.英国皇家空军的RBDCRD.大规模的并行模拟.多尺度建模模型的使用.

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